123 research outputs found
A Family of Maximum Margin Criterion for Adaptive Learning
In recent years, pattern analysis plays an important role in data mining and
recognition, and many variants have been proposed to handle complicated
scenarios. In the literature, it has been quite familiar with high
dimensionality of data samples, but either such characteristics or large data
have become usual sense in real-world applications. In this work, an improved
maximum margin criterion (MMC) method is introduced firstly. With the new
definition of MMC, several variants of MMC, including random MMC, layered MMC,
2D^2 MMC, are designed to make adaptive learning applicable. Particularly, the
MMC network is developed to learn deep features of images in light of simple
deep networks. Experimental results on a diversity of data sets demonstrate the
discriminant ability of proposed MMC methods are compenent to be adopted in
complicated application scenarios.Comment: 14 page
Topological Defects in the Abrikosov Lattice of Vortices in Type-II Superconductors
The free energy costs for various defects within an Abrikosov lattice of
vortices are calculated using the lowest Landau level approximation (LLL).
Defect solutions with boundary conditions for lines to meet at a point
(crossing defect) and for lines to twist around each other (braid defect) are
sought for 2, 3, 6, and 12 lines. Many results have been unexpected, including
the nonexistence of a stable two- or three-line braid. This, and the high
energy cost found for a six-line braid lead us to propose that the equilibrium
vortex state is not entangled below the irreversibility line of the high-
superconductors or in a large part of the vortex-liquid phase above this line.
Also, the solution for an infinite straight screw dislocation is found, and
used to give a limiting form for the free energy cost of very large braids.
This depends on the area enclosed by the braid as well as its perimeter length.Comment: 30 pages, 17 Encapsulated PostScript figures, uses Revtex (with epsf
A general scaling relation for the critical current density in Nb3Sn
We review the scaling relations for the critical current density (Jc) in
Nb3Sn wires and include recent findings on the variation of the upper critical
field (Hc2) with temperature (T) and A15 composition. We highlight deficiencies
in the Summers/Ekin relations, which are not able to account for the correct
Jc(T) dependence. Available Jc(H) results indicate that the magnetic field
dependence for all wires can be described with Kramer's flux shear model, if
non-linearities in Kramer plots are attributed to A15 inhomogeneities. The
strain (eps) dependence is introduced through a temperature and strain
dependent Hc2*(T,eps) and Ginzburg- Landau parameter kappa1(T,eps) and a strain
dependent critical temperature Tc(eps). This is more consistent than the usual
Ekin unification, which uses two separate and different dependencies on Hc2*(T)
and Hc2*(eps). Using a correct temperature dependence and accounting for the
A15 inhomogeneities leads to a remarkable simple relation for Jc(H,T,eps).
Finally, a new relation for s(eps) is proposed, based on the first, second and
third strain invariants.Comment: Accepted Topical Review for Superconductor, Science and Technolog
Elasticity-driven interaction between vortices in type-II superconductors
The contribution to the vortex lattice energy which is due to the
vortex-induced strains is calculated covering all the magnetic field range
which defines the vortex state. This contribution is compared with previously
reported ones what shows that, in the most part of the vortex state, it has
been notably underestimated until now. The reason of such underestimation is
the assumption that only the vortex cores induce strains. In contrast to what
is generally assumed, both core and non-core regions are important sources of
strains in high- superconductors.Comment: 10 pages, 1 figure, revtex
Campbell Penetration Depth of a Superconductor in the Critical State
The magnetic penetration depth was measured in the presence
of a slowly relaxing supercurrent, . In single crystal
below approximately 25 K, is
strongly hysteretic. We propose that the irreversibility arises from a shift of
the vortex position within its pinning well as changes. The Campbell length
depends upon the ratio where is the critical current defined
through the Labusch parameter. Similar effects were observed in other cuprates
and in an organic superconductor
The Flux-Line Lattice in Superconductors
Magnetic flux can penetrate a type-II superconductor in form of Abrikosov
vortices. These tend to arrange in a triangular flux-line lattice (FLL) which
is more or less perturbed by material inhomogeneities that pin the flux lines,
and in high- supercon- ductors (HTSC's) also by thermal fluctuations. Many
properties of the FLL are well described by the phenomenological
Ginzburg-Landau theory or by the electromagnetic London theory, which treats
the vortex core as a singularity. In Nb alloys and HTSC's the FLL is very soft
mainly because of the large magnetic penetration depth: The shear modulus of
the FLL is thus small and the tilt modulus is dispersive and becomes very small
for short distortion wavelength. This softness of the FLL is enhanced further
by the pronounced anisotropy and layered structure of HTSC's, which strongly
increases the penetration depth for currents along the c-axis of these uniaxial
crystals and may even cause a decoupling of two-dimensional vortex lattices in
the Cu-O layers. Thermal fluctuations and softening may melt the FLL and cause
thermally activated depinning of the flux lines or of the 2D pancake vortices
in the layers. Various phase transitions are predicted for the FLL in layered
HTSC's. The linear and nonlinear magnetic response of HTSC's gives rise to
interesting effects which strongly depend on the geometry of the experiment.Comment: Review paper for Rep.Prog.Phys., 124 narrow pages. The 30 figures do
not exist as postscript file
The German National Registry of Primary Immunodeficiencies (2012-2017)
Introduction: The German PID-NET registry was founded in 2009, serving as the first national registry of patients with primary immunodeficiencies (PID) in Germany. It is part of the European Society for Immunodeficiencies (ESID) registry. The primary purpose of the registry is to gather data on the epidemiology, diagnostic delay, diagnosis, and treatment of PIDs.
Methods: Clinical and laboratory data was collected from 2,453 patients from 36 German PID centres in an online registry. Data was analysed with the software Stata® and Excel.
Results: The minimum prevalence of PID in Germany is 2.72 per 100,000 inhabitants. Among patients aged 1–25, there was a clear predominance of males. The median age of living patients ranged between 7 and 40 years, depending on the respective PID. Predominantly antibody disorders were the most prevalent group with 57% of all 2,453 PID patients (including 728 CVID patients). A gene defect was identified in 36% of patients. Familial cases were observed in 21% of patients. The age of onset for presenting symptoms ranged from birth to late adulthood (range 0–88 years). Presenting symptoms comprised infections (74%) and immune dysregulation (22%). Ninety-three patients were diagnosed without prior clinical symptoms. Regarding the general and clinical diagnostic delay, no PID had undergone a slight decrease within the last decade. However, both, SCID and hyper IgE- syndrome showed a substantial improvement in shortening the time between onset of symptoms and genetic diagnosis. Regarding treatment, 49% of all patients received immunoglobulin G (IgG) substitution (70%—subcutaneous; 29%—intravenous; 1%—unknown). Three-hundred patients underwent at least one hematopoietic stem cell transplantation (HSCT). Five patients had gene therapy.
Conclusion: The German PID-NET registry is a precious tool for physicians, researchers, the pharmaceutical industry, politicians, and ultimately the patients, for whom the outcomes will eventually lead to a more timely diagnosis and better treatment
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